NeuroSense Therapeutics
Market cap $3.2M 1.9M shares (vendor count, Nov 7, 2026) × $1.68 close Nov 6, 2026 · share count from the market-data vendor, not the SEC cover page
Most recent annual filing: 2026-03-31
- PrimeC filingDec 2026PrimeC filing, Dec 2026, notable
- NDS Canada filingMar 2027NDS Canada filing, Mar 2027, notable
- NRSN listing updateMar 2027NRSN listing update, Mar 2027, routine
- PrimeC Ph3 start3Q 2027PrimeC Ph3 start, 3Q 2027, notable
- PARAGON trial start3Q 2027PARAGON trial start, 3Q 2027, notable
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (3 active programs)
PrimeC
ciprofloxacin · celecoxib · ciprofloxacin/celecoxibStabiliC
ciprofloxacin · celecoxibCapital (as filed)
- Cash
- $166K cash and cash equivalents · Dec 31, 2025 (20-F)
- Operating cash flow
- −$1.9M annual ÷ 4, year to Dec 31, 2025 (20-F)
- As stated in coverage
- $231K cash per the update of Sep 25, 2026 — the company's own words as read there, not the filed figure
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (10)
- 2026-11-03 UPDATE: NeuroSense Therapeutics (NRSN) - Canada Slips to March 🔒 Paid
- 2026-10-27 UPDATE: NeuroSense Therapeutics (NRSN) - Selling the Drug Before the Trial 🔒 Paid
- 2026-10-02 UPDATE: NeuroSense Therapeutics (NRSN) - The Delisting Letter Arrives
- 2026-09-25 UPDATE: NeuroSense Therapeutics (NRSN) - Paying the Bills in Shares 🔒 Paid
- 2026-09-09 UPDATE: NeuroSense Therapeutics (NRSN) - The Ratio Is 1-for-20 🔒 Paid
- 2026-08-31 UPDATE: NeuroSense Therapeutics (NRSN) - PARAGON Gets Shrunk 🔒 Paid
- 2026-07-31 UPDATE: NeuroSense Therapeutics (NRSN) - The Reverse Split Goes on the Ballot
- 2026-07-30 UPDATE: NeuroSense Therapeutics (NRSN) - The Chasm Gets Papered
- 2026-07-22 UPDATE: NeuroSense Therapeutics (NRSN) - The Canada Card Gets Played
- 2026-07-11 NeuroSense Therapeutics (NRSN) — Scientific Deep Dive for PrimeC and Pipeline Products
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (10 calls)
Every verdict Biotech Distilled has published on NeuroSense Therapeutics, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-07-11 Avoid NeuroSense Therapeutics (NRSN) — Scientific Deep Dive for PrimeC and Pipeline Products Near-terminal balance sheet, going-concern risk, and the Relyvrio precedent dominate the genuinely interesting ALS biology, making the equity primarily a dilution vehicle until a strategic partnership or Phase-3-sized financing materializes.
- 2026-07-22 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - The Canada Card Gets Played Health Canada engagement is real but only one leg of a two-legged stool; without a strategic partnership or Phase-3-sized financing, the equity remains a dilution vehicle despite the modestly de-risked Canadian catalyst.
- 2026-07-30 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - The Chasm Gets Papered A live $3.79M ATM at $0.4802 with disclosed dilution, workforce cut to seven employees, and no partner confirm the equity is a dilution vehicle; neither tripwire has been cleared.
- 2026-07-31 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - The Reverse Split Goes on the Ballot A special meeting to authorize a 1-for-4 to 1-for-40 reverse split with authorized capital held at 200 million shares signals the split is a prerequisite for a dilutive raise, not a listing fix, and no tripwire has been cleared.
- 2026-08-31 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - PARAGON Gets Shrunk Redesigning PARAGON 'substantially smaller and shorter' optimizes for reaching a submission rather than definitively answering whether PrimeC works, and neither the partnership nor financing tripwire has been cleared.
- 2026-09-09 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - The Ratio Is 1-for-20 A 1-for-20 reverse split at the middle of the authorized band creates a 105:1 authorized-to-outstanding ratio to enable a dilutive raise, not to fix the underlying balance sheet, and no tripwire has been cleared.
- 2026-09-25 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - Paying the Bills in Shares PARAGON slipping to Q3 2027, vendor bills settled in stock consuming 12.8% of the post-split float, 'strategic alternatives' language added, and the $35M MVLS gap unsolved ahead of Tuesday's deadline make the equity increasingly uninvestable.
- 2026-10-02 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - The Delisting Letter Arrives A formal Nasdaq delisting determination with a 4.7x market-value gap and a $5M immediate-delisting floor only ~33% below the current price make the listing risk the dominant concern, eclipsing the science.
- 2026-10-27 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - Selling the Drug Before the Trial A pre-approval commercial channel with an unnamed equity-paid advisor produces no controlled evidence, may impede PARAGON enrollment, and does nothing to address the Nasdaq delisting process as the stock trades below the $5M immediate-delisting floor.
- 2026-11-03 Avoid UPDATE: NeuroSense Therapeutics (NRSN) - Canada Slips to March The Canadian NDS slipping to March 2027 pushes the main catalyst to the edge of the Nasdaq Panel's maximum window while the stock trades at roughly half the $5M immediate-delisting floor, making survival of the listing the dominant risk.
- Avoid call · opened Jul 13, 2026 at $14.60 · -88.5% vs XBI -2.0% (Nov 6, 2026)
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (3 quotes from 3 filings)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“This patent will expire in December 2042.”
matched to PrimeC · regulatory submission · read as December 2042
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“Final meeting minutes reflected alignment on the planned content and structure of the ALS submission, and the Company is now targeting an NDS filing in early December 2026, supported by the expanded PARADIGM clinical, survival and biomarker package.”
matched to NDS (Canada) · regulatory submission · read as December 2026
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“This is the approach we are taking in Canada, where, following our discussions with Health Canada, including the pre-NDS process, we are preparing a New Drug Submission (NDS) for PrimeC, which we currently expect to submit in December 2026.”
matched to PrimeC · trial initiation · read as December 2026
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (38)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from Aug 6, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 2, 2026ReleaseNeuroSense to Strengthen PrimeC Canadian ALS Submission With New NfL Data→ BD updateSummary on the 6-K
- Nov 2, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED NOVEMBER 2, 2026→ BD updateThe Canadian NDS deadline slipped three months to March 2027 — extending the one near-term catalyst into the Nasdaq Panel's maximum window — while new NfL biomarker data from PARADIGM provides a genuine, if incremental, scientific positive. The stock is down 38.6% week-over-week and now trading well below the $5M immediate-delisting floor.
- Oct 29, 2026ReleaseNeuroSense to Present Integrated Clinical and Biomarker Evidence Shaping PrimeC's Phase 3 Development at NEALS 2026BD extracted 1 program update from this document → NRSN pipeline
- Oct 26, 20266-KForeign issuer report→ BD updateNeuroSense has signed a collaboration to supply PrimeC through a U.S. pre-approval access pathway, targeting first revenues in H1 2027 — the first commercial arrangement since the March pharma term-sheet collapse, but one that pays the advisor in equity and carries enough "mays" and "potentials" to fill a risk-factor section.
- Oct 19, 2026ReleaseNeuroSense Files U.S. Patent Application for Traumatic Brain Injury
- Oct 19, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED OCTOBER 19, 2026
- Oct 13, 2026ReleaseNeuroSense Secures Nasdaq Hearing Date as PrimeC Approaches Key Regulatory and Funding Milestones
- Oct 13, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED OCTOBER 13, 2026BD extracted 1 program update from this document → NRSN pipeline
- Oct 2, 2026ReleaseNeuroSense Provides Update on Nasdaq Listing Compliance→ BD updateSummary on the 6-K
- Oct 2, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED OCTOBER 2, 2026→ BD updateThe September 29 Nasdaq deadline I flagged arrived exactly as predicted: bid-price compliance was cured by the 1-for-20 split, but the $35M MVLS deficiency triggered a formal Staff Determination — a delisting notice — and the stock cratered ~43% on the week. The company is appealing to a Hearings Panel, which stays trading but resolves nothing about the structural problem.BD extracted 1 program update from this document → NRSN pipeline
- Sep 28, 2026ReleaseNeuroSense to Participate in the 5th Annual ROTH Healthcare Opportunities Conference
- Sep 25, 2026ReleaseNeuroSense Provides Business Update and Progress for the First Half of 2026→ BD updateSummary on the 6-K
- Sep 25, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED SEPTEMBER 25, 2026→ BD updateNRSN has surged +1,633% since the 1-for-20 reverse split — with no new science and no financing disclosed — while today's H1 6-K puts $231K cash, a $1.99M six-month burn, and a newly disclosed Q3 2027 PARAGON timeline on the record.BD extracted 1 program update from this document → NRSN pipeline
- Sep 10, 2026ReleaseNeuroSense to Present at H.C. Wainwright 28th Annual Global Investment Conference
- Sep 9, 20266-KForeign issuer report→ BD updateNeuroSense just pulled the trigger on a 1-for-20 reverse split, effective Monday September 14 — the bear-case mechanism I've flagged across four consecutive posts is now a filed fact, arriving three weeks before the September 29 Nasdaq cure deadline with 200 million shares authorized and a live ATM still printing.
- Aug 31, 2026ReleaseThree-part program - AI-enabled characterization of PrimeC's formulation advantage, an active-comparator trial against edaravone, and a streamlined pivotal pathway - is designed to strengthen...→ BD updateNeuroSense just scrapped the original 300-patient PARAGON design and replaced it with a three-part "capital-efficient" program — a smaller/shorter pivotal, a head-to-head vs. edaravone, and AI-enabled PK modeling — while guiding a Canada NDS for December 2026. Whether this is a smart pivot or a forced retreat from a trial the company was never going to fund is the question that matters.BD extracted 1 program update from this document → NRSN pipeline
- Aug 27, 20266-KForeign issuer report
- Aug 13, 2026ReleaseNeuroSense Therapeutics Ltd. (NASDAQ: NRSN) ("NeuroSense"), a late-stage clinical biotechnology company focused on developing disease-modifying treatments for neurodegenerative diseases, today...
- Aug 13, 20266-KForeign issuer report · EX-99.1 CEO LETTER
- Aug 6, 2026ReleaseFinal meeting minutes reflect alignment with Health Canada on the planned content and structure of the ALS submission CAMBRIDGE, Mass., Aug. 6, 2026 /PRNewswire/ -- NeuroSense Therapeutics Ltd....BD extracted 1 program update from this document → NRSN pipeline
- Aug 6, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED AUGUST 6, 2026
- Jul 31, 20266-KForeign issuer report · EX-99.1 NOTICE AND PROXY STATEMENT FOR THE SPECIAL GENERAL MEETING OF SHAREHOLDERS OF TH
- Jul 31, 20266-KForeign issuer report
- Jul 22, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED JULY 22, 2026
- Jun 29, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED JUNE 29, 2026
- Jun 25, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED JUNE 25, 2026
- Jun 11, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED JUNE 11, 2026
- Jun 9, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED JUNE 9, 2026
- Jun 8, 20266-KForeign issuer report
- Apr 28, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED APRIL 28, 2026
- Apr 24, 20266-KForeign issuer report
- Apr 6, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED APRIL 6, 2026
- Apr 3, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED APRIL 3, 2026
- Mar 31, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE, DATED MARCH 31, 2026
- Mar 31, 202620-FAnnual report (foreign)
- Mar 24, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED MARCH 24, 2026
- Mar 16, 20266-KForeign issuer report · EX-99.1 PRESS RELEASE DATED MARCH 16, 2026
- Mar 11, 20266-KForeign issuer report
2 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Jul 31, 2026EFFECTRegistration effective
- Jul 30, 2026F-3/AF-3/A