Immunocore
Market cap $1.60B 51.7M shares (10-Q, Oct 31, 2026) × $30.99 close Nov 6, 2026
Most recent annual filing: 2026-02-25
- Brenetafusp Ph1 readout2H 2026Brenetafusp Ph1 readout, 2H 2026, notable
- IMC-P115C Ph1 interim2H 2026IMC-P115C Ph1 interim, 2H 2026, notable
- IMC-U120AI IND filing2H 2026IMC-U120AI IND filing, 2H 2026, notable
- Immatics anzu-cel SUPRAME topline1H 2027Immatics anzu-cel SUPRAME topline, 1H 2027, major
- IMC-M113V HIV Ph1 readout1H 2027IMC-M113V HIV Ph1 readout, 1H 2027, notable
- IMC-R117C PIWIL1-A02 Ph1 interim2027IMC-R117C PIWIL1-A02 Ph1 interim, 2027, notable
- PRISM-MEL-301 / ATOM corporate update2027PRISM-MEL-301 / ATOM corporate update, 2027, routine
- Tebentafusp TEBE-AM topline2Q 2027Tebentafusp TEBE-AM topline, 2Q 2027, thesis-defining
- ATOM enrollment done2028ATOM enrollment done, 2028, notable
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (15 active programs)
brenetafusp
IMC-F106Cbrenetafusp
IMC-P115C
- Undisclosed indication
IMC-R117C
IMC-M113V
IMC-I109V
IMC-S118AI
IMC-U120AI
KIMMTRAK
tebentafusp · tebentafusp-tebnTechnology platforms
ImmTAX
Immune mobilizing monoclonal TCRs Against X disease — modular bispecific TCR platform combining high-affinity engineered TCR targeting system with tailored effector functions (anti-CD3 for immune activation or PD1 agonist for immune suppression); broad disease focus across oncology, infectious diseases, and autoimmune diseases
ImmTAC
Immune mobilizing monoclonal TCRs Against Cancer — soluble TCR bispecific biologics engineered to recognize intracellular cancer antigens with ultra-high affinity and kill tumor cells via anti-CD3 immune-activating effector function; applicable to hematologic and solid tumors regardless of mutational burden or immune infiltration
Targets: CD3, gp100, PRAME
ImmTAV
Immune mobilizing monoclonal TCRs Against Viruses — infectious disease sub-platform of ImmTAX; bispecific soluble TCR molecules with high specificity for low-expression viral antigens combined with anti-CD3 effector; focus on HIV and HBV functional cure
Targets: CD3
ImmTAAI
Immune mobilizing monoclonal TCRs Against AutoImmune disease — bispecific platform designed for tissue-specific down-modulation of the immune system via PD-1 receptor agonism; disease focus: autoimmune diseases including type 1 diabetes and inflammatory dermatological diseases
Targets: PD1
ImmTAX · Gates Foundation
Proprietary, flexible, off-the-shelf T cell receptor bispecific (ImmTAC/ImmTAV) platform for cancer, infectious diseases, and autoimmune diseases; enables soluble TCR bispecific therapeutic candidates
Capital (as filed)
- Cash
- $512M cash and cash equivalents · Sep 30, 2026 (10-Q)
- Short-term investments
- $389M Sep 30, 2026
- Operating cash flow
- $20.1M quarter Jun 30, 2026 → Sep 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $880M cash per the update of Oct 7, 2026 — the company's own words as read there, not the filed figure
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (3)
- 2026-11-07 UPDATE: Immunocore (IMCR) - The Binary Slips, the Combo Speaks
- 2026-10-08 UPDATE: Immunocore (IMCR) - Fidelity Heads for the Exit 🔒 Paid
- 2026-09-18 Immunocore Holdings (IMCR) — Scientific Deep Dive for KIMMTRAK, Brenetafusp and the ImmTAX Pipeline 🔒 Paid
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (3 calls)
Every verdict Biotech Distilled has published on Immunocore, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-09-18 Speculative buy speculative Immunocore Holdings (IMCR) — Scientific Deep Dive for KIMMTRAK, Brenetafusp and the ImmTAX Pipeline At ~$1.2B enterprise value, the funded TEBE-AM binary offers asymmetric exposure to a marketed biologic with a real cash floor, but the two re-rating catalysts rest on a 60-patient open-label cohort and a six-patient combination into a post-PD-1 market that just gained an approved HLA-unrestricted competitor.
- 2026-10-08 Speculative buy speculative UPDATE: Immunocore (IMCR) - Fidelity Heads for the Exit Fidelity's ~60% stake cut reinforces sizing caution but does not change the funded binary or KIMMTRAK floor; the speculative buy is maintained with emphasis on keeping powder dry rather than chasing.
- 2026-11-07 Speculative buy speculative UPDATE: Immunocore (IMCR) - The Binary Slips, the Combo Speaks TEBE-AM slips to Q2 2027 and KIMMTRAK growth decelerates to ~10%, but the cash floor is intact and the 17-patient gp100+PRAME combination data adds a credible franchise-extension path; 'speculative' still applies with the readout now further away.
- Long call · opened Sep 18, 2026 at $32.00 · -3.2% vs XBI -2.9% (Nov 6, 2026)
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (1 quote from 1 filing)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“The trial is event-driven and topline overall survival data is expected in the second quarter of 2027.”
matched to Tebentafusp (TEBE-AM) · topline data · read as second quarter of 2027
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (13)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from Oct 15, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 6, 2026ReleaseImmunocore presents promising data from Phase 1/2 trial cohort evaluating brenetafusp plus KIMMTRAK® (tebentafusp-tebn) in metastatic uveal melanoma→ BD updateSummary on the 8-K
- Nov 6, 2026ReleaseImmunocore reports third quarter financial results and provides a business update→ BD updateSummary on the 8-K
- Nov 6, 20268-KCurrent report: results of operations · EX-99.1→ BD updateTEBE-AM's OS readout just slipped to Q2 2027 — the fourth milestone re-date on the most important catalyst in the company — while fresh SITC data show the KIMMTRAK + brenetafusp combination produced a 70% two-year OS rate in 17 first-line mUM patients, and Q3 revenue printed its first nominal year-over-year decline.
- Nov 6, 202610-QQuarterly report→ BD updateSummary on the 8-K
- Oct 29, 2026ReleaseImmunocore will present Phase 1 data for brenetafusp plus KIMMTRAK® (tebentafusp-tebn) in metastatic uveal melanoma, during a late-breaking oral session at the 2026 SITC meetingPhase 1 data for brenetafusp + KIMMTRAK in metastatic uveal melanoma — the first two-T-cell-engager combination ever tested in a solid tumor — drops at SITC on November 6–7, a catalyst not on the published calendar and one that could tell us something real about whether layering PRAME on top of gp100 adds signal.
- Oct 15, 2026ReleaseImmunocore announces first patient dosed in the Phase 1 trial of IMC-S118AI – its first tissue-specific autoimmune candidate – for patients with type 1 diabetesThe first tissue-tethered PD-1 agonist to enter the clinic just dosed its first patient — a named catalyst from the deep dive that arrives as institutional sellers dominate the headlines, and quietly confirms the ImmTAAI platform is more than a slide deck.BD extracted 1 program update from this document → IMCR pipeline
- Sep 14, 20268-KCurrent report: Reg FD disclosure · EX-99.1
- Aug 6, 20268-KCurrent report: results of operations · EX-99.1
- Aug 6, 202610-QQuarterly report
- May 27, 20268-KCurrent report: shareholder vote
- May 6, 20268-KCurrent report: results of operations · EX-99.1 EXHIBIT 99.1
- May 6, 202610-QQuarterly report
- Apr 16, 2026DEF 14AProxy statement
9 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Oct 7, 2026SCHEDULE 13G/A13G amendment→ BD updateFMR LLC (Fidelity) has cut its IMCR stake by roughly 60% — from ~4.3M shares (8.8%) to ~1.74M shares (3.6%) — joining T. Rowe Price in a significant institutional trim ahead of the TEBE-AM OS readout. Two of the largest holders in the quality roster have now materially reduced exposure into the binary.
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 13, 2026SCHEDULE 13G/A13G amendment
- Aug 6, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13GPassive >5% holder (13G)
- May 8, 2026S-8Employee plan registration
- Apr 16, 2026ARSAnnual report to shareholders
- Mar 6, 2026SCHEDULE 13G/A13G amendment