4D-150
Gene Therapy Target: VEGF-A, VEGF-B, VEGF-C, PlGF
Most recent annual filing: 2026-03-18
Directed evolution platform applied in non-human primate models to generate diverse libraries of ~1 billion synthetic AAV capsid sequences and select customized evolved vectors targeting specific tissues; disease focus includes retina and lung diseases
Articles open on Substack. Some deep dives are subscriber-only.