BriaCell Therapeutics

BCTX Lead: Phase 3 6 Biotech Distilled articles ↓

Most recent annual filing: 2025-10-16

Catalyst timeline

Bria-IMT + CPI Ph3 interim2026Bria-IMT + CPI Ph3 interim, 2026, major

Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.

Pipeline (7 active programs)

Bria-IMT

SV-BR-1-GM

Cell Target: GM-CSF, PD-1

Metastatic Breast Cancer Phase 3 Incyte NCT03066947

Bria-OTS

Bria-BRES · Bria-BRES+

Cell Target: PD-1

Metastatic Breast Cancer Phase 1 BeiGene NCT06471673

Soluble CD80

sCD80 · soluble CD80 · BP-80

Protein Target: CD80, CTLA4, PD-L1

Undisclosed indication Preclinical University of Maryland, Baltimore County

Technology platforms

TILsRx

Proprietary platform designed to activate tumor-infiltrating lymphocytes (TILs) within the tumor microenvironment; integrates T cell engagers and immune checkpoint modulators; multivalent technology enables simultaneous engagement of multiple cancer-associated and immune pathway targets; focus areas include prostate, lung, breast, pancreatic, and ovarian cancers; early agents include antibodies to B7-H3

Targets: B7-H3

Bria-TILsRx

Quadrivalent multi-specific binding reagents designed as potent immune cell activators and/or immune checkpoint inhibitors; selectively target and destroy cancer cells while minimizing effects on normal cells; focus on immuno-oncology across multiple cancer types

Targets: B7-H3

Bria-OTS+

Off-the-shelf cellular immunotherapy platform using premanufactured, HLA-matched, genetically modified whole-cell cancer vaccine lines designed to activate innate and adaptive immunity; basis for Bria-MEL+ (melanoma), Bria-PROS+ (prostate cancer), and Bria-OTS (breast cancer) programs.

Biotech Distilled coverage (6)

2026-06-02 UPDATE: BriaCell (BCTX) — The War Chest Wasn’t Full After All
2026-03-15 UPDATE: BriaCell (BCTX) – The War Chest is Full and AACR is on Deck 🔒 Paid
2026-02-21 UPDATE: BriaCell (BCTX) – A Safety Nod and a Corporate Shell Game 🔒 Paid
2026-01-31 UPDATE: BriaCell (BCTX) Drops the Receipts on Super Responders 🔒 Paid
2026-01-14 UPDATE: BriaCell (BCTX) Just Gave Us a Masterclass in Pump and Raise 🔒 Paid
2026-01-09 BriaCell (BCTX): Scientific Deep Dive for Bria-IMT™ and Pipeline Products 🔒 Paid

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