Modular protein technology platform for generating monospecific and bispecific immunotherapeutic proteins; single-chain polypeptides with customized binding domains and Fc region; focus on oncology and potentially inflammatory diseases

ADAPTIR-FLEX

Heterodimer platform technology extending ADAPTIR to create protein therapeutics with varied specificity and valency; two-polypeptide hetero-dimer design enabling binding to up to four targets; supports trispecific molecules; focus on oncology including hard-to-treat solid tumors

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2026-06-16 Aptevo Therapeutics (APVO) - Scientific Deep Dive for Mipletamig, ALG.APV-527, and the ADAPTIR Pipeline

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