Spruce Biosciences

1. TA-ERT tralesinidase alfa BLA filing4Q 2026TA-ERT tralesinidase alfa BLA filing, 4Q 2026, major
2. TA-ERT tralesinidase alfa AdCom1H 2027TA-ERT tralesinidase alfa AdCom, 1H 2027, thesis-defining
3. TA-ERT tralesinidase alfa PDUFA date1H 2027TA-ERT tralesinidase alfa PDUFA date, 1H 2027, thesis-defining

Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.