EDG-15400
Small Molecule Target: cardiac sarcomere
Edgewise Therapeutics
Most recent annual filing: 2026-02-26
- mavacamten competitor Ph3 start2026mavacamten competitor Ph3 start, 2026, routine
- EDG-7500 FDA feedback2H 2026EDG-7500 FDA feedback, 2H 2026, material
- sevasemten topline4Q 2026sevasemten topline, 4Q 2026, material
- EDG-7500 Ph3 start4Q 2026EDG-7500 Ph3 start, 4Q 2026, notable
- aficamten competitor sNDA filing4Q 2026aficamten competitor sNDA filing, 4Q 2026, notable
- EWTX corporate updateNov 5, 2026EWTX corporate update, Nov 5, 2026, routine
- EDG-7500 readout1H 2027EDG-7500 readout, 1H 2027, material
- BHB-1893 competitor Ph3 start1H 2027BHB-1893 competitor Ph3 start, 1H 2027, routine
- EDG-003 corporate update2027EDG-003 corporate update, 2027, routine
- EDG-15400 Ph2 readout2H 2027EDG-15400 Ph2 readout, 2H 2027, material
- aficamten competitor interim2H 2027aficamten competitor interim, 2H 2027, notable
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Pipeline (3 active programs)
EDG-7500
Small Molecule Target: cardiac sarcomere
Technology platforms
muscle focused drug discovery platform
Proprietary muscle-focused drug discovery platform using custom high-throughput and translatable systems measuring integrated muscle function in whole organ extracts to identify small molecule precision medicines regulating key proteins in muscle tissue; focused on rare neuromuscular and cardiac diseases including muscular dystrophies and cardiometabolic diseases.
Targets: sarcomere modulators, myosin
EDG-003
Cardiometabolic discovery program targeting novel cardiometabolic targets; preclinical stage; part of Edgewise's broader muscle-focused drug discovery platform
Discontinued (1)
- sevasemten — Becker Muscular Dystrophy · divested to Servier as part of sale of muscular dystrophy business
Biotech Distilled coverage (1)
- 2026-09-30 Edgewise Therapeutics, Inc. (EWTX) — Scientific Deep Dive for EDG-7500, EDG-15400 and Pipeline Products 🔒 Paid
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