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CD19 (18 companies · 86 programs)

Companies with an active program directed at CD19.

Autolus Therapeutics plc AUTL

  • AUCATZYL — Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia Approved
  • AUCATZYL — Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia Phase 2
  • AUCATZYL — Diffuse Large B-Cell Lymphoma Phase 1
  • AUCATZYL — Chronic Lymphocytic Leukemia Phase 1
  • AUCATZYL — Follicular Lymphoma Phase 1
  • AUCATZYL — Primary Central Nervous System Lymphoma Phase 1
  • AUCATZYL — Systemic Lupus Erythematosus Phase 1
  • AUCATZYL — Lupus Nephritis Phase 2
  • AUCATZYL — Progressive Multiple Sclerosis Phase 1
  • AUTO1/22 — Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia Phase 1
  • AUTO8 — Relapsed/Refractory Multiple Myeloma Phase 1
  • AUTO8 — Light Chain Amyloidosis Phase 1

Century Therapeutics, Inc. IPSC

  • CNTY-308 — Systemic Lupus Erythematosus Preclinical
  • CNTY-308 — Lupus Nephritis Preclinical
  • CNTY-308 — Idiopathic Inflammatory Myopathy Preclinical
  • CNTY-308 — Diffuse Cutaneous Systemic Sclerosis Preclinical
  • CNTY-101 — Systemic Lupus Erythematosus Phase 1
  • CNTY-101 — Lupus Nephritis Phase 1
  • CNTY-101 — Idiopathic Inflammatory Myopathy Phase 1
  • CNTY-101 — Diffuse Cutaneous Systemic Sclerosis Phase 1
  • CNTY-308

Cabaletta Bio, Inc. CABA

  • resecabtagene autoleucel — Systemic Lupus Erythematosus Phase 1
  • resecabtagene autoleucel — Lupus Nephritis Phase 1
  • resecabtagene autoleucel — Dermatomyositis Phase 1
  • resecabtagene autoleucel — Immune-Mediated Necrotizing Myopathy Phase 1
  • resecabtagene autoleucel — Systemic Sclerosis Phase 1
  • resecabtagene autoleucel — Generalized Myasthenia Gravis Phase 1
  • resecabtagene autoleucel — Pemphigus Vulgaris Phase 1
  • resecabtagene autoleucel — Autoimmune Diseases Phase 1

Kyverna Therapeutics, Inc. KYTX

  • mivocabtagene autoleucel — Stiff Person Syndrome NDA Submitted
  • mivocabtagene autoleucel — Generalized Myasthenia Gravis Phase 3
  • mivocabtagene autoleucel — Progressive Multiple Sclerosis Phase 1
  • mivocabtagene autoleucel — Rheumatoid Arthritis Phase 2
  • mivocabtagene autoleucel — Lupus Nephritis Phase 1
  • KYV-102 Phase 1
  • KYV-201 Preclinical

Nkarta, Inc. NKTX

  • NKX019 — Lupus Nephritis Phase 1
  • NKX019 — Primary Membranous Nephropathy Phase 1
  • NKX019 — Systemic Sclerosis Phase 1
  • NKX019 — Idiopathic Inflammatory Myopathy Phase 1
  • NKX019 — ANCA-Associated Vasculitis Phase 1
  • NKX019 — Systemic Lupus Erythematosus Phase 1
  • NKX019 — Myasthenia Gravis Phase 1

Artiva Biotherapeutics, Inc. ARTV

  • AlloNK — Rheumatoid Arthritis Phase 1
  • AlloNK — Sjögren's Disease Phase 2
  • AlloNK — Systemic Sclerosis Phase 2
  • AlloNK — Idiopathic Inflammatory Myopathies Phase 2
  • AlloNK — Systemic Lupus Erythematosus Phase 1
  • AlloNK — Lupus Nephritis Phase 1

Xencor Inc XNCR

  • XmAb657 — Idiopathic Inflammatory Myopathies Phase 1
  • obexelimab — Relapsing Multiple Sclerosis Phase 2
  • obexelimab — Immunoglobulin G4-Related Disease NDA Submitted
  • obexelimab — Systemic Lupus Erythematosus Phase 2
  • Monjuvi — Diffuse Large B-Cell Lymphoma Approved
  • Monjuvi — Follicular Lymphoma Approved

Climb Bio, Inc. CLYM

  • budoprutug — Primary Membranous Nephropathy Phase 2
  • budoprutug — Immune Thrombocytopenia Phase 2
  • budoprutug — Systemic Lupus Erythematosus Phase 1
  • budoprutug — Systemic Lupus Erythematosus Phase 1
  • budoprutug — Primary Membranous Nephropathy Phase 1

ADC Therapeutics SA ADCT

  • ZYNLONTA — Diffuse Large B-Cell Lymphoma Approved
  • ZYNLONTA — Marginal Zone Lymphoma Phase 2
  • ZYNLONTA — Follicular Lymphoma Phase 2
  • ZYNLONTA — Pediatric B-Cell Non-Hodgkin Lymphoma Phase 2

Allogene Therapeutics, Inc. ALLO

  • cemacabtagene ansegedleucel — Large B-Cell Lymphoma Phase 2
  • ALLO-329 — Systemic Lupus Erythematosus Phase 1
  • ALLO-329 — Idiopathic Inflammatory Myopathies Phase 1
  • ALLO-329 — Systemic Sclerosis Phase 1

Cullinan Therapeutics, Inc. CGEM

  • CLN-978 — Systemic Lupus Erythematosus Phase 1
  • CLN-978 — Rheumatoid Arthritis Phase 1
  • CLN-978 — Sjögren's Disease Phase 1
  • CLN-978 — Lupus Nephritis Phase 2

Zenas BioPharma, Inc. ZBIO

  • obexelimab — IgG4-Related Disease NDA Submitted
  • obexelimab — Relapsing Multiple Sclerosis Phase 2
  • obexelimab — Systemic Lupus Erythematosus Phase 2
  • ZB014 Preclinical

Caribou Biosciences, Inc. CRBU

  • vispacabtagene regedleucel — Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma Phase 1
  • vispacabtagene regedleucel — Relapsed/Refractory Large B Cell Lymphoma Phase 1
  • vispacabtagene regedleucel — Large B-Cell Lymphoma Phase 3

ImmunityBio, Inc. IBRX

  • CD19 t-haNK — Non-Hodgkin Lymphoma Phase 1
  • CD19 t-haNK — Waldenström Macroglobulinemia Phase 1

IN8BIO, INC. INAB

  • INB-619 — Systemic Lupus Erythematosus Preclinical